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Pemphigus is the Latin term used to describe blisters on the skin. This is an uncommon disease that can affect many people but is more common in the elderly. When you have this disease, you will have blisters on your body, arms or legs. Blisters can appear in the eyes, nose, mouth, or genitals. The cause of pemphigus is not fully understood and there is no cure. However, we have measures to help treat the disease to avoid frequent infections and recurrences. In this article, SignsSymptomsList will present the causes and symptoms of pemphigus.
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1. What is pemphigus?
Pemphigus is an acquired autoimmune disease in which the body produces an antibody called an autoantibody. It is this autoantibody that attacks the cells of the skin and mucous membranes and forms a blister.
Pemphigus pathology is classified into several different subtypes. All forms of the disease have the common manifestation of a rash and blisters. However, they differ in the location of the blisters on the body and the way they appear. Therefore, the way to diagnose and treat also varies depending on the type of disease. Of all the forms, common pemphigus is the most common.
In general, pemphigus is not as common as other dermatological conditions. The incidence is about 30/1,000,000 people, which means 30 out of 1,000,000 people have pemphigus.
The disease can affect many different people and ages. However, women are affected more often than men. Women are almost twice as likely to get the disease as men. Any age can develop autoimmune bullous disease. But surveys show that the average age of the disease ranges from 40 to 60 years old. This means that the disease usually affects the elderly or elderly.
2. Causes of disease
Pemphigus is an autoimmune disease, meaning it's caused by our own immune system. Normally, when the body is exposed to foreign elements from the environment, the immune system will identify them as foreign objects compared to the body. From there, the body will secrete antibodies to destroy these foreign objects to protect us from harmful effects.
In pemphigus, the body produces antibodies for some unknown reason. It is this antibody that destroys the cells of the skin. As a result, the cells are no longer adherent to each other, but loosely form bubbles.
>> You can see more about the effect of the disease on pregnant women: Pemphigus (autoimmune blisters) in pregnant women .
The reason why our bodies secrete antibodies is not well understood. There are a number of factors that play a role in triggering an outbreak, including:
The cause of the body's own antibody production is not well understood
People with other autoimmune diseases such as lupus, psoriasis or rheumatoid arthritis are also at risk for pemphigus. In particular, the elderly or the elderly and women will be more susceptible to the disease.
3. Expression
The common manifestations of autoimmune bullous bodies are:
4. When to see a doctor?
There are many conditions that can cause blisters on the skin. Therefore, when blisters appear on the skin, especially large ones, you should quickly see a doctor. At that time, your doctor will examine you and diagnose whether you have pemphigus.
You should see a doctor when you see blisters appear on your skin
5. How is pemphigus diagnosed?
The dermatologist will examine the blisters on the skin to see if they have pemphigus features. In addition, your doctor may recommend that you perform some more professional tests to help diagnose the disease accurately. That is the skin biopsy test. The doctor will take a skin sample from the blister and test it. Also, your doctor may recommend that you have a blood test to look for certain antibodies that are associated with pemphigus.
6. Pemphigus is classified into what types of disease?
Pemphigus pathology is classified into several different subtypes. The forms of pemphigus are:
There are 3 types of pemphigus disease
These are the characteristics that help distinguish the bodies quickly. To be sure, you need to see your doctor.
7. Treatment
Because the cause of the disease is not fully understood, there is no cure for pemphigus. At the onset of the disease, measures are applied with the aim of:
When pemphigus blisters appear, the patient will be treated as follows:
>> See more: What are corticosteroids? Consequences of corticosteroid abuse .
There is currently no cure for the disease
8. How is the disease monitoring regime?
Because pemphigus is not curable, we must have a monitoring and control regimen. Patients should be careful not to stop taking the drug or reduce the dose on their own. This will make the disease worse or harder to control.
If you have been diagnosed with pemphigus in the past, during follow-up you should see your doctor when:
Before the period of treatment with corticosteroids, almost patients died from blisters causing dehydration, malnutrition or infection. However, when treated with corticosteroids, the prognosis of the disease is better. The general condition of the disease improved with the time of treatment. The longer the treatment period, the higher the chance of complete healing. However, the disease can recur at any time. If you have the blisters come back after the treatment period or the first blisters are not explained, you should also see a doctor for timely treatment.
Doctor Vo Thi Ngoc Hien
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