How is Exforge (valsartan, amlodipine) used in the treatment of high blood pressure?

Exforge (valsartan, amlodipine) is indicated for the treatment of high blood pressure, a common disease in the elderly. So what is Exforge, indicated in what cases, what are the side effects of the drug and how to use it? SignsSymptomsList will introduce what Exforge is through the article below!

Active ingredients of the drug Exforge : valsartan, amlodipine.

Medicines containing similar ingredients : Amlo-plus, Valzomix

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• 1. What is Exforge (valsartan, amlodipine)?
• 2. In which cases is Exforge (valsartan, amlodipine) indicated?
• 3. How do I use Exforge (valsartan, amlodipine) to be effective?
• 4. Who should not take Exforge (valsartan, amlodipine)?
• 5. Exforge (valsartan, amlodipine) side effects
• 6. Interactions of Exforge (valsartan, amlodipine) with other drugs
• 7. How should Exforge be preserved?

1. What is Exforge (valsartan, amlodipine)?

To find out what Exforge is, we need to know that the drug has two active ingredients: valsartan and amlodipine , which have vasodilating effects, helping to lower blood pressure and prevent angina.

Drugs Exforge

2. In which cases is Exforge (valsartan, amlodipine) indicated?

It is indicated in patients with essential hypertension that is not controlled by a single drug (amlodipine or valsartan).

3. How do I use Exforge (valsartan, amlodipine) to be effective?

The drug is available in two strengths: 5 mg amlodipine/80 mg valsartan and 10 mg amlodipine/160 mg valsartan . Depending on the patient's blood pressure control status, the doctor will have appropriate indications. Patients need to strictly follow the doctor's instructions in all cases to get the best results.

• Exforge 5/80 is used in patients whose blood pressure is not adequately controlled with amlodipine 5 mg or valsartan 80 mg as monotherapy.
• Exforge 10/160 is used in patients whose blood pressure is not adequately controlled with amlodipine 10 mg or valsartan 160 mg as monotherapy.

4. Who should not take Exforge (valsartan, amlodipine)?

• People who are hypersensitive to the ingredients of the drug.
• People with severe liver failure, cirrhosis, or cholestasis.
• Pregnant women in the second and third trimesters of pregnancy.
• The patient has severe hypotension.
• The patient is in shock (including cardiogenic shock).
• Patients with obstructive heart problems such as hypertrophic obstructive cardiomyopathy, severe aortic stenosis.
• Patients with heart failure after acute myocardial infarction.

5. Exforge (valsartan, amlodipine) side effects

Common side effects of the drug include:

• Nasopharyngitis, flu, headache
• Edema 
• Blushing

6. Interactions of Exforge (valsartan, amlodipine) with other drugs

• Care should be taken when using the drug concurrently with other antihypertensive drugs such as acebutolol, carteolol, carvedilol...
• Antihypertensive side effects such as tricyclic antidepressants, drugs to treat benign prostatic hyperplasia.
• It is not recommended to use amlodipine with grapefruit
• Do not use Exforge concurrently with antiviral drugs indinavir, ritonavir...
• Antifungal azoles such as: ketoconazole
• Antibiotics erythromycin or clarithromycin
• Be careful when using with anticonvulsants: carbamazepine, phenobarbital, phenytoin, fosphenytoin, primidone...
• If amlodipine is co-administered with simvastatin, the recommended dose of Simvastatin is 20 mg/day
• Dantrolene (infusion) used with Exforge increases the risk of hyperkalemia.
• Concomitant use with NSAIDs reduces the antihypertensive effect of Exforge.

7. How should Exforge be preserved?

• Store in a dry place away from direct light.
• Keep Exforge out of reach of children.

Exforge has two active ingredients, valsartan and amlodipine. Both drugs have the same antihypertensive effect, but by different mechanisms. Although SignsSymptomsList has provided information about what Exforge is, its use needs to be prescribed by a Cardiologist. During use, if you have any unusual symptoms, please notify your doctor immediately for timely intervention.

You can consult:

• What you need to know about the heart drug Herbesser (diltiazem)
• Blood pressure control with Valsartan (Diovan, Valsacard): Effects and precautions
• What is Nifedipine (Adalat)? Uses, uses and side effects