What is Fraizeron? and information to note

What is Fraizeron (secukinumab)? In what cases is Fraizeron used? What should be noted about possible side effects while taking the drug? Let's take a closer look at SignsSymptomsList about Fraizeron in the article analyzed below!

Active ingredient: secukinumab
Drugs with similar ingredients: Consentyx,..

content

• What is Fraizeron?
• Uses of Fraizeron
• Fraizeron should not be used if:
• How to use Fraizeron effectively?
• Dosage of Fraizeron
• Side effects
• Interactions that occur when taking Fraizeron
• Precautions while using Fraizeron
• Special Uses
• Fraizeron overdose treatment
• What to do when you miss a dose of Fraizeron
• Methods of preservation

What is Fraizeron?

• Fraizeron contains the active ingredient secukinumab.
• Secukinumab is a monoclonal antibody, an immunosuppressant that inhibits interleukin.
• More specifically, secukinumab works by inhibiting the release of pro-inflammatory cytokines (before the induction of inflammation), chemokines, and mediators of damaged tissues.
• Thereby, reducing IL-17A (interleukin 17A)-mediated involvement in autoimmune and inflammatory diseases.

Uses of Fraizeron

• It is indicated for the treatment of moderate to severe plaque psoriasis in patients for whom systemic therapy or phototherapy has been indicated.
• In addition, Fraizeron is used in active psoriatic arthritis but has not responded adequately to antirheumatic drugs alone or in combination with methotrexate.
• Not only that, secukinumab is also used in the treatment of active ankylosing spondylitis and inadequate response to conventional therapy. Learn more about this disease at the article:  Ankylosing spondylitis: Causes, symptoms and treatment directions.

Fraizeron should not be used if:

Hypersensitivity to secukinumab or to any of the other ingredients in the formulation of Fraizeron.

How to use Fraizeron effectively?

• Subcutaneously.
• Take care to avoid areas with psoriasis.

Dosage of Fraizeron

The following is a reference dose when treating adults. The patient needs to follow the exact course of treatment prescribed by the doctor

• Plaque psoriasis
  + Start with 300 mg at week 0, 1, 2 and 3.
  + Then maintain monthly dose starting from week 4.
• Treatment of psoriatic arthritis
  If the patient has concomitant moderate to severe plaque psoriasis or has an incomplete response to anti-TNFα
  +++ Initiate a dose of 300 mg.
  +++ Initiate at weeks 0, 1, 2 and 3.
  +++ Then maintain monthly dose from week 4.
  For other patients
  +++ Start dose of 150 mg at week 0, 1, 2 and 3.
  +++ Thereafter, maintain the monthly dose of Fraizeron from week 4.
• Ankylosing spondylitis
  + Start taking the drug at a dose of 150 mg, starting at weeks 0, 1, 2 and 3.
  + Then maintain the monthly dose from week 4.

Refer to the article:  Psoriasis: What should and should not be eaten?

Side effects

• Upper respiratory tract infections.
• Patients infected with oral herpes , inguinal fungus.
• Otitis externa, skin or mucosal candidiasis , ocular conjunctivitis, runny nose, diarrhea, urticaria.
• Patients may develop neutropenia (mild, transient, and reversible).

Interactions that occur when taking Fraizeron

• Note, do not use Fraizeron concurrently with live vaccines.
• In addition, there are no human interaction studies yet.

Precautions while using Fraizeron

• Note in patients with chronic infection, history of recurrent infection, Crohn's disease, liver or kidney failure.
• In addition, in patients with active TB infection, Fraizeron should not be used
• Consider using TB medicine before starting treatment.
• For pregnant or lactating women, use with caution.
• To date, there are not enough safety and efficacy data in patients <18t="">
• Not only that, the drug may also increase the risk of upper respiratory tract infections (mild-moderate, not requiring discontinuation of treatment).
• Skin-mucosal candidiasis (non-severe).

Special Uses

Women of pregnancy age

• Women of childbearing age should use effective contraception during treatment and for at least 20 weeks after treatment.

Pregnant

• There are insufficient data on the use of Fraizeron in pregnant women.
• It is best to avoid administering secukinumab to pregnant women to avoid the risk of harm to the mother and fetus.

See also:  Things to note during pregnancy .

Breastfeeding Women

• It is not known whether secukinumab is excreted in human milk and whether immunoglobulins excreted in human milk are absorbed systemically after ingestion.
• Therefore, because of the potential adverse reactions experienced with secukinumab in breast-feeding, breastfeeding should be discontinued during and 20 weeks after treatment. 
• Or stopping treatment with secukinumab should be weighed against the benefits of breast-feeding and secukinumab treatment for the mother.

Driving and operating machinery

• Up to now, there have been no reports of dizziness or headaches when using Fraizeron.
• Therefore, Fraizeron can be used in subjects who drive and use these machines.

Fraizeron overdose treatment

• In clinical studies, there have been no reports of overdose to date.
• In case of overdose, it is necessary to monitor the patient carefully so that when any abnormal signs and symptoms are detected, there will be timely systemic treatment measures.

What to do when you miss a dose of Fraizeron

• This is a drug that is given by injection and is administered by medical professionals (doctor/pharmacist).
• Therefore, missed dose in this case is very rare, so follow the schedule prescribed by the doctor.

Methods of preservation

• Keep Fraizeron out of the reach of children and pets.
• Store the medicine in a cool, dry place. Avoid exposure to direct light or keep the medicine in humid places.
• The best storage temperature is 2 – 8 ºC.

Above is the information on the use of Fraizeron. Call your doctor immediately if you have any unusual symptoms so that they can be treated and supported promptly!