Composition and some common side effects of 5-in-1 vaccine

Immunizations have become indispensable when a new child is born. Immunizations help the body build immunity and protect children against viruses and bacteria. In Vietnam, vaccination with 5-in-1 vaccine brings many benefits to children. Let's learn more about the 5-in-1 vaccine with SignsSymptomsList and the common side effects of the 5-in-1 vaccine through the article below.

content

• What is a 5-in-1 vaccine?
• What kind of 5-in-1 vaccine is available?
• Ingredients of the 5-in-1 vaccine
• 5-in-1 vaccine dose for children
• Some common side effects of 5-in-1 vaccine
• Taking care of children after vaccination

What is a 5-in-1 vaccine?

The 5-in-1 vaccine is 5 vaccines that protect against 5 different diseases and are combined in just 1 shot. Thereby, proactively protect children from the top 5 dangerous diseases. The diseases the 5-in-1 vaccine can prevent depends on the different vaccines.

What kind of 5-in-1 vaccine is available?

The 5-in-1 vaccine has 3 types including Pentaxim (France), ComBE Five (India) and Quinvaxem (Korea). The above vaccines are used in a state-funded (free) expanded immunization program or a service immunization program. Before looking at the common side effects of 5-in-1 vaccines , let's take a closer look at the available 5-in-1 vaccines.

Extended vaccination program

• Previously, the Quinvaxem vaccine produced by Berna Biotech, South Korea, was used in a free immunization program for children. Quinvaxem vaccine is the most common vaccine recommended by the World Health Organization (WHO). Currently, the manufacturer has discontinued the production of Quinvaxem vaccine.

Quinvaxem vaccine is a 5-in-1 vaccine

• Therefore, the Ministry of Health has converted the use of Quinvaxem vaccine with the ComBE Five vaccine (India). ComBE Five is a 5-in-1 vaccine similar in composition and efficacy to Quinvaxem. 400 million doses of ComBE Five vaccine have been used in more than 43 countries worldwide.

ComBE Five . 5-in-1 vaccine

Service Immunization Program

• Pentaxim vaccine manufactured by Sanofi Pasteur, France is a newer generation 5-in-1 vaccine compared to Quinvaxem and ComBE Five. To date, Pentaxim vaccine has been used in 99 countries around the world.

Pentaxim is made in France

Ingredients of the 5-in-1 vaccine

Quinvaxem vaccine, Korea

• Quinvaxem contains antigens from dead or weakened bacteria, diphtheria, tetanus, pertussis, hepatitis B and Hib viruses. These antigens prompt the body to produce an immune response to protect itself from diphtheria, tetanus, pertussis, hepatitis B, and Hib-induced diseases.
• The pertussis ingredient in Quinvaxem is whole-cell pertussis. This vaccine is purified from pertussis bacteria after being grown in proliferative media and euthanized.

ComBE Five Vaccine, India

• ComBE Five can prevent diphtheria, tetanus, whooping cough, hepatitis B, and pneumonia or meningitis caused by H.influenzae type B (Hib) because it contains dead or weakened antigens of these viruses. These bacteria and viruses.
• Like Quinvaxem, the pertussis component in the ComBE Five vaccine is whole-cell pertussis.

Pentaxim vaccine, France

• Pentaxim contains antigens of bacteria viruses of diphtheria, tetanus, pertussis, polio and H.influenzae type B (Hib). Therefore, Pentaxim helps prevent diseases such as diphtheria, tetanus, whooping cough, polio and pneumonia and meningitis caused by Hib.
• The pertussis ingredient in Pentaxim is acellular pertussis. This vaccine contains a specific antigenic component after eliminating other unnecessary antigenic components of this bacterium.
• Less common side effects with Pentaxim 5-in-1 vaccine and fewer fever symptoms than with the other two 5-in-1 vaccines due to the acellular pertussis component.

In addition, the 5-in-1 vaccine also contains preservatives, excipients, additives, growth medium or antibiotics with the effect of ensuring safety and effectiveness in disease prevention.

5-in-1 vaccine dose for children

All three vaccines above are recommended to be given to children early. When children from 6 weeks old, parents need to monitor and closely follow the vaccination schedule. The dose of the 5-in-1 vaccine should be adhered to as follows:

• The 3 basic injections are spaced at least 28 days apart and should be given before 1 year of age.
  • 1st dose: injection for children at 2 months old
  • 2nd dose: injection for children at 3 months old
  • 3rd dose: injection for children at 4 months old
• The booster shot is given to children when they are 12-24 months old.

Children should be vaccinated according to the vaccination schedule

Some common side effects of 5-in-1 vaccine

Some of the common side effects of the 5-in-1 vaccine are as follows:

• Mild fever, less than 38.5 degrees Celsius.
• Crying and irritable.
• Difficulty sleeping, loss of appetite, lazy to breastfeed.
• Painful swelling and redness at the injection site.

In 1-2 days, symptoms caused by a common side effect of the 5-in-1 vaccine should resolve on their own. In case the above symptoms persist, you need to take the child to the nearest medical facility.

Taking care of children after vaccination

• Immediately after vaccination, children must stay at the vaccination facility for 30 minutes for observation. This helps to ensure timely handling if any abnormalities occur.
• After returning home, parents need to observe and check their children regularly. Pay special attention to monitoring at night for 24 hours after injection.
• Parents should be careful not to press or touch the injection site of the child.
• When the injection site is painful or red, you should not apply anything to the injection site.
• Monitor the child's temperature, the child's eating and sleeping activities, and the child's mental health.
• Absolutely do not arbitrarily use antipyretic or other drugs.

The article contains information about 5-in-1 vaccines given to children. It should be noted that the 5-in-1 vaccine to prevent diseases depends on each different vaccine. Parents need to monitor the vaccination schedule as well as the child's symptoms after vaccination to promote the effectiveness of the vaccine and ensure the safety of the child. When experiencing unusual reactions after injection, it is necessary to take the child to the nearest medical facility to receive advice from doctors and medical staff.