Synflorix pneumococcal vaccine (Belgium): Uses, dosage, side effects

Synflorix pneumococcal vaccine provides active immunization for infants 6 weeks to 5 years of age. This vaccine can help prevent illnesses caused by Streptococcus pneumoniae in children. In which, typically diseases such as meningitis syndrome, pneumonia, bacteremia and acute otitis media. What precautions should be taken when administering the pneumococcal Synflorix vaccine?  

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• Uses of the pneumococcal vaccine Synflorix
• How much does the Synflorix pneumococcal vaccine cost?
• Diseases likely to occur when not vaccinated with pneumococcal Synflorix
• Synflorix pneumococcal vaccine schedule
• Notes when administering pneumococcal vaccine Synflorix
• Possible side effects of the pneumococcal vaccine Synflorix
• Synflorix . pneumococcal vaccine interactions

Uses of the pneumococcal vaccine Synflorix

Synflorix pneumococcal vaccine is administered to children aged 6 weeks to 5 years.

This vaccine, after being given, can help prevent diseases caused by pneumococcal serotypes 1, 4, 5, 6B, 7F, 9V, 14, 19F and 23F. Specific diseases include:

• The child has an infection.
• Meningitis disease .
• Cases of pneumonia.
• Blood infection.
• Acute otitis media.

In addition, after vaccination, children can actively prevent acute otitis media caused by bacteria Haemophilus influenza of unspecified type.

Pneumococcal vaccine Synflorix

How much does the Synflorix pneumococcal vaccine cost?

According to VNVC vaccination center, the cost of Synflorix pneumococcal vaccine has a reference price as shown in the table below:

Diseases likely to occur when not vaccinated with pneumococcal Synflorix

If your child is not vaccinated with the pneumococcal Synflorix vaccine, he or she can get one of the following diseases. That is:

Disease caused by pneumococcal serotypes 1, 4, 5, 6B, 7F, 9V, 14, 19F and 23F:

• Infection.
• Meningitis.
• Cases of pneumonia.
• Blood infection.
• Acute otitis media.

In addition, children can develop acute otitis media caused by Haemophilus influenzae bacteria of unspecified type.

Synflorix pneumococcal vaccine schedule

The schedule for the Synflorix pneumococcal vaccine is different for each child depending on the age of the child:

Children 6 weeks - 6 months old

The 3 + 1 course is recommended for optimal results:

• The first dose can be started at 6 weeks of age.
• Administer the 2nd dose at least 1 month after the 1st dose.
• Then, the 3rd dose is given at least 1 month after the 2nd dose.
• Give a booster shot at least 6 months after the 3rd injection.

The 2 + 1 vaccination course   is used to replace the 3 +1 regimen:

• The first dose can be started at 6 weeks of age.
• Administer the second dose at least 2 months after the first injection.
• Give a booster shot at least 6 months after the 2nd injection.

Note: for premature babies, at least from 27 weeks of age, attention should be paid to:

• Administer Synflorix vaccine at 2 months of age.
• It is recommended to use the basic 3 + 1 regimen presented above.

Vaccination schedule by age for children

Children from 7 months - 11 months old

• Take the first injection at the time prescribed by the doctor.
• The second dose is given at least 1 month after the first dose.
• Give a booster dose of Synflorix pneumococcal vaccine when the child is > 1 year old. Note, the booster dose is at least 2 months after the second dose.

For older children 1-5 years old and not previously vaccinated

• Apply a schedule of 2 doses of Synflorix pneumococcal vaccine to children.
• With the 2nd injection at least 2 months after the first injection.
• Note, there is no need for a booster shot.

Notes when administering pneumococcal vaccine Synflorix

Before, during and after the injection, it is necessary for the doctor to carefully examine the child. Note, vaccination is only performed when prescribed by a doctor to avoid unexpected cases. Specifically, these are the cases:

• Synflorix pneumococcal vaccine is contraindicated in children with hypersensitivity to the vaccine components.
• Postponing vaccination for children with acute high fever.
• Note, Synflorix pneumococcal vaccine should not be administered intravenously or intradermally under any circumstances.
• In addition, care should be taken when injecting children with thrombocytopenia or blood disorders
• It should be noted: administration of the pneumococcal Synflorix vaccine is not a substitute for routine immunization with diphtheria, tetanus and Hib vaccines.
• For children who are immunocompromised or are taking immunosuppressive drugs, there may be a decrease in the level of antibody response to active immunity.
• Children at high risk of diseases caused by pneumococcal disease should be vaccinated from the age <2>
• Not only that, pay attention to the risk of apnea and need to monitor breathing within 48-72 hours after the vaccination is indicated:
  + For premature babies, babies ≤ 28 weeks of pregnancy.
  Especially for children with previous breathing problems.
• For medical staff, it is necessary to prepare means to prevent anaphylaxis when vaccinating children.

Possible side effects of the pneumococcal vaccine Synflorix

Some unwanted effects when using Synflorix pneumococcal vaccine for children that parents need to know to handle.

Frequent

• Children show signs of anorexia.
• Dizziness condition.
• The child has pain, redness, and swelling at the injection site.
• May have a high fever >38 ºC.

Other less common side effects such as

• The condition of the child is hardened at the injection site.
• High fever >39 ºC.

Possible side effects after vaccination

Serious side effects

Watch out for the following rare but very serious side effects that need careful monitoring if they occur

• Atopic dermatitis.
• Children with atypical dermatitis, eczema.
• There may be convulsions and not due to fever.
• Rash, urticaria.
• Decreased tone, decreased response.

Synflorix . pneumococcal vaccine interactions

Synflorix pneumococcal vaccine can be given simultaneously with other vaccines such as:

• Diphtheria, acellular pertussis, hepatitis B vaccines.
• Inactivated polio vaccine.
• Vaccines against diseases caused by Hib.
• Hepatitis B vaccines.
• Measles - mumps-rubella vaccines .
• Chickenpox vaccine.
• Note the meningococcal vaccine.
• Rotavirus vaccine.

However, although there is no interaction, the child needs to be vaccinated at a different site from where the pneumococcal vaccine was given.

In summary, parents need to take their children to immunization centers to be carefully examined and screened before deciding to vaccinate against pneumococcal Synflorix . In addition, must pay attention to monitor the health of the child after the injection, if there is anything abnormal, take the child to the hospital for timely treatment!