Everything you need to know about Feburic

What is Feburic? How is Feburic drug indicated in pathological cases? How to use it and what are the things to keep in mind throughout the course of taking the drug? Let's find out and analyze what Feburic is with SignsSymptomsList through the article below!

Active ingredient name : febuxostat.

Brand names : Uloric, Febustad, Febuxat…

content

• 1. What is Feburic?
• 2. Instructions for taking Feburic
• 3. Feburic drug side effects
• 4. Contraindications of Feburic
• 5. Notes when using Feburic
• 6. Drug interactions when taking Feburic
• 7. For special subjects
• 8. What to do when you miss a dose of Feburic
• 9. Handling when taking too much Feburic
• 10. How to store medicine

1. What is Feburic?

Feburic is a pill that is used to reduce the production of uric acid in the human body. A buildup of uric acid can cause symptoms of gout .

• Febuxostat is used to keep uric acid levels from getting too high in people with gout.
• Febuxostat is only used for people who cannot take allopurinol or when allopurinol is not effective.
• In addition, febuxostat may also be used for purposes not listed in this medication guide.
• The drug should be used after an acute gout attack has subsided.

>> Besides taking medication, you should also equip yourself with the necessary knowledge to make the gout treatment process more effective. Read more: What should people with gout eat and avoid?

Feburic drug

2. Instructions for taking Feburic

• Initial dose: 40mg/time/day. If serum uric acid level is greater than 6mg/dL after 2 weeks, increase dose to 80mg once daily.
• Maintenance dose: 40-80mg/time/day.
• Maximum dose: 80mg/time/day.

Uric acid levels can be checked as early as 2 weeks after starting the medication.

Use only in people who do not respond to the maximum dose of allopurinol, who are intolerant to allopurinol, who should not be treated with allopurinol.

3. Feburic drug side effects

Common side effects:

• Gout flare, joint pain.
• Nausea .
• Mild rash.
• Liver problems.

Rare serious side effects:

• Allergies (rash, difficulty breathing, swelling of the face, throat).
• Severe skin reactions (fever, sore throat, burning eyes, skin pain, redness, widespread skin rash causing blistering and peeling).

Call your doctor right away if you have:

• Feeling faint.
• Symptoms of heart attack, angina, tachycardia, shortness of breath .
• Stomach pain, unusual tiredness, dark urine, jaundice.
• Signs of a stroke, sudden weakness (especially on one side of the body), severe headache, slurred speech, vision and balance problems.

4. Contraindications of Feburic

• Allergy to any ingredient in the medicine.

5. Notes when using Feburic

• You are taking azathioprine, mercaptopurine, theophylline.
• Talk to your doctor if you have ever had heart problems, a heart attack, a stroke, liver or kidney disease, an organ transplant, Lesch-Nyhan syndrome (an inherited condition that causes uric acid levels to rise in the blood). high blood pressure, joint pain, and problems with movement and behavior).
• Tell your doctor if you are planning to become pregnant, are pregnant or breast-feeding.
• Consider and consult a doctor if giving this medicine to children or the elderly.

If you have heart problems, you need to tell your doctor before taking the medicine

6. Drug interactions when taking Feburic

The drug has many interactions with other drugs. You should tell your doctor if you are using:

• Azathioprine, Mercaptopurine (febuxostat may increase blood levels of azathioprine, mercaptopurine to toxic levels).
• Leflunomide, Lomitapide, Mipomersen, Pexidartinib, Teriflunomide (using these drugs together with febuxostat can cause liver problems).
• Theophylline (febuxostat changes the way theophylline is broken down, increasing blood levels of theophylline).

Interaction with diseases: secondary hyperuricemia , renal dysfunction, liver failure, coronary artery disease.

7. For special subjects

Pregnant

According to the US FDA, Feburic is not indicated for pregnant women because of the potential risk to humans.

According to Australia's Therapeutic Goods Administration, Feburic is classified in group B1, which is a drug used only in a small number of pregnant women without increasing the frequency of malformations or other direct or indirect effects on the fetus.

In an embryonic study in rats, the drug crossed the placental barrier and was present in fetal tissue. However, the drug has not been shown to adversely affect the health of the fetus or newborn.

Breastfeeding Women

This medicine passes easily into breast milk (according to rat studies).

Before taking medication, always consult with your doctor to weigh the benefits and risks.

8. What to do when you miss a dose of Feburic

• If you miss a dose, take it as soon as you remember.
• Do not take a double dose to make up for a missed dose.
• In case it is almost time for the next dose, skip the missed dose and take it according to the normal schedule.

9. Handling when taking too much Feburic

Doctors or emergency medical care lines should be contacted immediately.

10. How to store medicine

• Store in a dry place at 15-30°C. Avoid direct light.
• Avoid leaving the medicine in a humid place such as a bathroom.
• Keep the medicine out of the reach of children and pets.
• Expired drugs must not be used and these drugs must be treated before being released into the environment.

Feburic is a drug taken in tablet form to reduce the production of uric acid in the human body. A buildup of uric acid can cause symptoms of gout. If in the process of using the drug appear many side effects that seriously affect the body, call your doctor immediately for support and advice!

Pharmacist Hoang Thuy Tien