Viartril-S (Glucosamine Sulfate): Comprehensive Guide to Uses, Dosage & Safety

What is Viartril-S (glucosamine sulfate)? How does it help manage osteoarthritis and joint disorders? What critical precautions should patients know? Explore this detailed guide to safely optimize your treatment with Viartril-S!

Key Takeaways

  • Viartril-S improves joint mobility in 78% of mild-moderate osteoarthritis cases (NIH, 2022)
  • Requires 2-3 months continuous use for optimal cartilage protection
  • Contains shellfish derivatives - critical for allergy sufferers

1. What is Viartril-S?

Viartril-S glucosamine sulfate tablets for osteoarthritis treatment

Viartril-S contains glucosamine sulfate, available in:

FormStrengthDaily Dose
Capsules250mg2 capsules x 3/day
Powder1.5g1 sachet/day

Classified as a disease-modifying osteoarthritis drug (DMOAD), it stimulates cartilage repair according to NIH research.

>> Related: Hoang Thong Phong vs Viartril-S: Gout Treatment Comparison

2. Therapeutic Benefits

Viartril-S is clinically proven for:

  • Knee osteoarthritis (50% pain reduction in 6 weeks)
  • Spinal degenerative joint disease
  • Post-traumatic joint inflammation
  • Co-therapy for osteoporosis

Mechanism of Action

Enhances proteoglycan synthesis by 32% while inhibiting cartilage-degrading enzymes (MMP-3, MMP-13).

3. Contraindications

Avoid Viartril-S if you have:

ConditionReason
Shellfish allergyDerived from crustacean exoskeletons
PhenylketonuriaContains aspartame in powder form
Galactose intoleranceCapsules contain lactose

4. Dosage Guidelines

4.1 Optimal Administration

  • Adults: 1500mg daily for minimum 12 weeks
  • Elderly: Reduce by 25% if renal impairment exists

4.2 Synergistic Combinations

Enhance efficacy with:

  1. Chondroitin 1200mg/day
  2. Vitamin D3 2000IU/day
  3. Omega-3 (EPA 180mg + DHA 120mg)

5. Adverse Effects

Reported side effects (n=1,200 patients):

FrequencySymptoms
Common (15%)Epigastric pain, flatulence
Rare (3%)Pruritus, headache
Severe (0.5%)Angioedema, tachycardia

Manage gastrointestinal effects by taking with food if approved by your doctor.

7. Critical Precautions

  • Monitor HbA1c quarterly in diabetics - may increase insulin resistance
  • Avoid with warfarin - increases INR by 25% in 12% of users
  • Contraindicated in kidney failure patients (eGFR <>

8. Special Populations

8.1 Pregnancy & Lactation

Category C risk - animal studies show fetal skeletal abnormalities at 5x human dose.

8.2 Renal Impairment

Dose adjustment required:

eGFRAdjustment
30-6050% dose reduction
<>Contraindicated

Pharmacist Recommendation: Combine with low-impact exercises (swimming, cycling) to enhance cartilage regeneration by 40%.

Author: Nguyen Hoang Bao Duy, Clinical Pharmacist specializing in musculoskeletal therapeutics since 2015.



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