Everything you need to know about the stomach medicine Kagasdine (omeprazol)

What is Kagasdine (omeprazole)? What is Kagasdine (omeprazol) used for? What should be noted about possible side effects while taking the drug? Let's learn with SignsSymptomsList carefully about Kagasdine (omeprazol) in the article analyzed below!

Active ingredient: omeprazole .

Drugs with similar ingredients: Agimepzol; AG-Ome; Akatwo; Amnopra; Ampharco Omeprazole; Atimezol; Ausmezol; Baromezole; Bestaprazole; Biolamezole; Braficozol; Cadimezol; Dudecer; Durosec; Eselan; Eurometac; Faskit 40; Futanol; Gastroprazone; Getzome; Gitazot; Glomezol;…

content

• What is Kagasdine?
• How much does Kagasdine cost?
• The effect of the drug Kagasdine
• Cases when Kagasdine should not be used
• Instructions for taking Kagasdine 
• Kagasdine side effects
• Drug interactions when taking Kagasdine
• Precautions while using Kagasdine
• Special subjects using drugs
• Treatment of Kagasdine overdose
• What to do when you miss a dose of Kagasdine
• How to store medicine?

What is Kagasdine?

The active ingredient omeprazole is a benzimidazole with substituents attached, with similar structure and effect as pantoprazol, lansoprazole, esomeprazole.

Kagasdine (omeprazol) works by inhibiting gastric acid secretion by inhibiting the hydrogen/potassium adenosine triphosphatase enzyme system, also known as the proton pump, in the parietal cells of the stomach.

In addition, Omeprazole may inhibit Helicobacter pylori in patients with duodenal ulcer and/or reflux esophagitis infected with this bacterium.

The combination of omeprazole with some antibacterial drugs such as clarithromycin , amoxicillin can eradicate H. pylori with ulcer healing and long-term remission.

Kagasdine (omeprazole)

How much does Kagasdine cost?

• Dosage form: Capsules.
• Packing: Box of 2 blisters x 10 tablets.
• Price of Kagasdine 20mg: 15,000 VND/box.

Note: Prices are for reference only. May change from time to time and depend on the supplier.

You can find this drug at many drugstores nationwide. However, you should choose to buy from reputable places to ensure quality and get specific advice from a doctor/pharmacist.

The effect of the drug Kagasdine

What disease does Kagasdine (omeprazole) treat? For the drug Kagasdine is indicated for use in the following diseases:

• Used in indigestion due to increased acid secretion.
• Treatment of gastroesophageal reflux disease .
• Cases of peptic ulcer disease .
• In addition, Kagasdine is used to treat Zollinger-Ellison syndrome.
• Not only that, the drug also helps to prevent stress ulcers, ulcers caused by non-steroidal anti-inflammatory drugs.

Cases when Kagasdine should not be used

Are allergic to omeprazole or to any of the ingredients in the formulation.

Instructions for taking Kagasdine 

1. Usage

• Kagasdine (omeprazol) is available in oral tablet form. Therefore, the tablet must be swallowed whole, without breaking, chewing or crushing.
• Must take the drug on an empty stomach, can be taken 1 hour before eating.

2. Dosage

To ease acid-related indigestion

Take omeprazole daily at a dose of 10 - 20 mg for 2 - 4 weeks.

Treatment of gastroesophageal reflux disease

• Usual dose: 20 mg omeprazole / time for 4 weeks.
• Then another 4 to 8 weeks if still not fully healed.
• In difficult-to-treat esophagitis, a daily dose of 40 mg may be used.

Maintenance treatment of esophagitis after healing is 20 mg / time / day and in the case of acid reflux is 10 mg / day.

Peptic ulcer

• Take a daily dose of 20-40 mg in severe cases.
• If duodenal ulcer, treatment is continued for 4 weeks, and for gastric ulcer is 8 weeks.

Elimination of H. pylori in peptic ulcer disease

• It is possible to combine omeprazole with antibacterial drugs in a 3-4 drug regimen.
• The triple regimen consisted of omeprazole 20 mg twice daily or 40 mg once daily, in combination with amoxicillin 1 g and clarithromycin 500 mg, both orally twice a day.
• In case the 3-drug regimen is effective, add bismuth to the regimen. These regimens are taken for 1 week. Only omeprazole can be continued for another 4 to 8 weeks.

Note, the dose of Kagasdine (omeprazol) is for reference only. Therefore, the exact dose prescribed by the doctor must be adhered to on a case-by-case basis. Absolutely do not arbitrarily increase or decrease the dose or use the wrong indication to limit the occurrence of side effects affecting health.

Kagasdine side effects

• Headache, drowsiness , dizziness.
• Diarrhea, nausea, vomiting, abdominal pain, constipation, bloating.
• Insomnia, sensory disturbances, fatigue.
• Urticaria, itching. a rash.
• transient increase in transaminases.
• Sweating , peripheral edema, hypersensitivity including angioedema, anaphylaxis.
• Leukopenia, thrombocytopenia, reduction in all blood cell lines, agranulocytosis, autoimmune hemolytic anemia.
• Reversible confusion, agitation, depression , hallucinations in elderly patients and especially in critically ill patients, hearing disorders.
• Causes large breasts in men.
• Gastritis, Candida infection, dry mouth.
• Hepatitis with or without jaundice, encephalopathy - liver disease in people with liver failure.
• Bronchospasm.
• Joint pain, muscle pain.
• Interstitial nephritis.
• In addition, proton pump inhibitors may increase the risk of gastrointestinal infections by inhibiting gastric acid secretion.

Side effects of the drug Kagasdine can cause drowsiness and dizziness

Drug interactions when taking Kagasdine

• Ciclosporin in the blood.
• Diazepam .
• Phenytoin .
• Warfarin.
• Dicoumarol.
• Nifedipine .
• Clarithromycin .

Precautions while using Kagasdine

• Note, before giving omeprazole to patients with gastric ulcers, the possibility of malignancy must be excluded.
• No dosage adjustment is necessary in elderly subjects.
• In patients with renal impairment, the effectiveness of omeprazole is not significantly changed.

However, in patients with liver failure, the elimination of the drug is slowed down. Therefore, a daily dose of 20 mg omeprazole is usually sufficient for these patients.

In addition, the use of proton pump inhibitors may increase the risk of gastrointestinal infections (Salmonella, Campylobacter).

Special subjects using drugs

Pregnant women

Some animal studies have not shown that omeprazole has the potential to cause malformations and toxicity to the fetus. Clinically, to date, no harmful effects on the fetus have been observed.

However, the follow-up time is not enough to rule out all risks to decide whether the drug is safe to use in this subject or not. Therefore, it is necessary to consider very carefully before deciding to use Kagasdine in this subject.

Breastfeeding Women

Omeprazole is distributed in breast milk. Therefore, consideration should be given to discontinuing the drug or stopping breast-feeding when taking the drug.

Driving and operating machinery

Kagasdine drug causes side effects on the central nervous system such as drowsiness, headache, dizziness, etc. Therefore, caution should be taken when using this product on subjects who drive and operate machinery to ensure safety at work. .

Treatment of Kagasdine overdose

Oral doses up to 160 mg/time, intravenous dose of 80 mg/time, intravenous dose of 200 mg/day and dose of 520 mg/day are still well tolerated.

In the literature, 2 cases of omeprazole overdose have been reported.

The main clinical manifestations of overdose are:

• Sleepy.
• Headache.
• Heart beats fast.

However, both patients recovered without any complications and did not require any special treatment.

What to do when you miss a dose of Kagasdine

• Use as soon as you remember that you have missed a dose.
• If the missed dose is close to the next dose. Skip the missed dose and follow the dosing schedule.
• Do not take a double dose to make up for the missed dose.

How to store medicine?

• Keep Kagasdine stomach medicine out of reach of children and pets.
• Store the medicine in a cool, dry place. Avoid exposure to direct light or keep the medicine in humid places.
• The best storage temperature is <30>

The above is the information about the use of Kagasdine in the treatment of acid indigestion, gastroesophageal reflux disease, etc. Call your doctor immediately if you have any unusual symptoms so that you can get medical help. timely handling and support!