Nautamine (diphenhydramine) anti-motion sickness drug: How to use it correctly?

Nautamine (diphenhydramine) is a medicine used by people who often suffer from motion sickness. So what is Nautamine, how is it used, what are the side effects and precautions? Let's find out with SignsSymptomsList through the article below.

Active ingredient name : (diacefyllin) diphenhydramine.
Similar brand name: Dramotion.

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1. What disease does Nautamine treat?

First, to answer the question of what Nautamine is , we need to know that Nautamine is indicated for use in adults and children over 2 years old to prevent and treat motion sickness.

Nautamine (diphenhydramine) anti-motion sickness drug: How to use it correctly?

Nautamine drug

2. How to use Nautamine to be effective?

2.1. How many Nautamine tablets do I need to take to work?

  • Adults and children > 12 years: Take 1 - 1.5 Nautamine tablets each time and repeat after 6 hours (if necessary). Do not take more than 6 tablets/day.
  • Children 6-12 years old: Take 1 Nautamine tablet each time and repeat after 6 hours (if necessary). Do not take more than 4 tablets/day.
  • Children from 2 to 6 years old: Take 1/2 Nautamine tablet each time and repeat after 6 hours (if necessary), k. Do not take more than 2 tablets a day. You must note that 1/2 tablet of Nautamine should be crushed and mixed with a little water before giving it to children under 6 years of age.

2.2. How to take Nautamine in the right way?

  • Take Nautamine with a sufficient amount of water.
  • Should take the medicine 30 minutes before taking the train.

Nautamine (diphenhydramine) anti-motion sickness drug: How to use it correctly?

Medicines to help fight motion sickness

3. Who should not take Nautamine?

Nautamine is contraindicated for the following subjects:

  • Children under 2 years old (due to the form of the drug is not suitable for children).
  • Glaucoma (glaucoma).
  • Difficulty urinating (due to prostate disease or other causes).
  • Hypersensitivity to any of the ingredients of the drug.
  • Nautamine should not be used by women while breastfeeding or while you are being treated with the antibiotic enoxacin, unless directed by your doctor.

4. What should be noted when using Nautamine?

  • Patients with long-term liver and kidney problems should notify their doctor to adjust the dose.
  • For the elderly, the drug should only be taken after consulting a doctor because Nautamine can cause constipation , dizziness or drowsiness. In addition, caution should be exercised when administering the drug to people at high risk of prostate disease.

5. What are the side effects of Nautamine? 

5.1. Allergic reaction

  • Skin rash (erythema, eczema, purpura, urticaria).
  • Quincke's edema: hives (rash) and sudden swelling of the face and neck, which can lead to difficulty breathing.
  • Hypersensitivity shock.

5.2. Leukopenia

May present with recurrent fever, with or without signs of infection.

5.3. Thrombocytopenia

May appear with manifestations such as nosebleeds, bleeding gums.

5.4. Other unwanted effects

  • Memory loss, concentration loss, dizziness (common in the elderly).
  • Drowsiness, decreased alertness, tremors, poor machine control.
  • Confusion, hallucinations, astigmatism.
  • Dry mouth, urinary retention, constipation.
  • Palpitations, low blood pressure.
  • Signs of arousal: anxiety, restlessness, insomnia (rare).

Nautamine can cause dizziness, drowsiness, and decreased alertness, especially when taken with alcohol. Therefore, you must not drink alcohol or other beverages or drugs containing alcohol while taking Nautamine. You need to be aware of this side effect if you are a driver or someone who needs to concentrate on driving and operating machinery.

Nautamine (diphenhydramine) anti-motion sickness drug: How to use it correctly?

Care should be taken when using Nautamine because of side effects

6. Can pregnant and lactating women use Nautamine?

  • For pregnant women: Nautamine can still be taken during pregnancy but should only be taken for a few days at the recommended dose. In late pregnancy, excessive use of Nautamine can affect the unborn baby.
  • For women who are breast-feeding: the drug is excreted in breast milk, so Nautamine should not be used while breastfeeding.

As a general rule, you should always consult your doctor before using Nautamine or any other medication during pregnancy and breast-feeding.

>> In addition to taking Nautamine, pregnant women should also be careful when taking other drugs during pregnancy. See also the article Antidepressants: Is it safe during pregnancy?

Nautamine (diphenhydramine) anti-motion sickness drug: How to use it correctly?

Pregnant women should be careful when taking the drug

7. How to deal with Nautamine overdose?

When overdose, especially when taking Nautamine with alcohol or phenothiazines, symptoms of central nervous system depression such as dizziness, convulsions, respiratory depression, difficulty urinating may appear. Extrapyramidal symptoms, sinus rhythm increase, atrioventricular block, prolongation of the QT interval... may appear late.

To solve

Contact your doctor or go to the nearest medical facility right away if you suspect you have overdosed on Nautamine. First aid measures include gastric lavage, use of activated charcoal, and induction of vomiting. Circulatory-respiratory support therapy may be considered if needed. Treatment with diazepam in case of convulsions. In the presence of severe hallucinogenic symptoms, physostigime may be used.

8. How much does Nautamine cost?

Currently on the market, the reference price of Nautamine is in the range of 2,000 - 3,500 VND/tablet. 

9. How to store Nautamine?

Store the medicine below 30°C, away from moisture and light.

Nautamine is an oral anti-motion sickness medication with the active ingredient diphenhydramine . SignsSymptomsList has provided you with the necessary information about what Nautamine is, but its use should be used after consulting a doctor, pharmacist. You should go to the clinic and hospital if you have strange symptoms during the use of the drug.

Pharmacist Tran Van Thy


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