What you need to know about Praxilen (naftidrofuryl)

Elderly people often experience complications due to peripheral vascular occlusion, impaired cognitive ability, affecting quality of life. In these cases, the use of Praxilen is often prescribed. Why should you take this medicine? How does Praxile work? Let's find out information about Praxylene (naftidrofuryl) with SignsSymptomsList.

Main active ingredient: naftidrofuryl.

Medicines containing similar ingredients: Stadfuryl, Orinadol, Naftizine.

The drug has two strengths, 100 mg and 200 mg, the 200 mg content is more commonly used.

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1. What is Praxylene (naftidrofuryl)?

Praxylene is a drug that belongs to the group of drugs with peripheral vasodilator effects. Drugs that work:

  • Decreased platelet aggregation (reduced congestion).
  • Vasodilation enhances blood circulation, improves the ability to circulate oxygen in the blood.

2. Indications of the drug Praxilen 

Praxilen is used to treat problems caused by chronic peripheral artery occlusion, such as:

  • Tissue necrosis
  • Nocturnal cramps
  • Raynaud's syndrome
  • Intermittent limping pain
  • Cyanosis of the extremities (ischemia to the extremities) and arterial problems in patients with diabetes.
  • Symptomatic treatment of cognitive decline and chronic neurosensory disorders in the elderly (except in cases of Alzheimer's disease and other dementias).

3. Instructions for taking Praxilen 

Depending on the doctor's prescription, the patient can take different doses.

  • Peripheral vascular problems: 1-2 tablets once, 3 times a day. Each course of such treatment lasts at least 3 months depending on the clinical response of the patient. (the highest dose is 600 mg naftidrofuryl/day).
  • Cognitive and sensory impairment in the elderly: 1 tablet (200mg) twice a day.

You should take the tablet whole without chewing with plenty of water (minimum 1 glass of water).

Praxilen should not be used in children, people with hypersensitivity to any of the ingredients, a history of increased oxaluria or recurrent kidney stones.

4. Notes when using Praxylene (naftidrofuryl)

What you need to know about Praxilen (naftidrofuryl)

  • Do not take medication to treat high blood pressure
  • If you take the medicine without drinking water before going to bed, it can cause esophagitis.
  • It is necessary to drink a lot of water when taking the drug because the drug can change the composition of urine, the risk of kidney stone formation.
  • Patients with galactoseemia or glucose-galactose malabsorption syndrome, lactase deficiency, should not use Praxilen.

There are currently no reports of other drug interactions with Praxilen. However, you need to inform your doctor about the drugs you are taking so that the doctor can consider when prescribing treatment.

5. For pregnant and lactating women

Indications for the treatment of Praxilen are common diseases in the elderly. There is no basis to study the safety level on pregnant and lactating women, so the drug should not be used for this special group of people.

6. Undesirable effects of the drug Praxylene (naftidrofuryl)

As with other drugs, when using Praxilen, you may experience unwanted side effects such as:

  • Skin: causes skin rashes.
  • Digestive system: you may have diarrhea, nausea, vomiting, epigastric pain. Especially if you take the medicine before going to bed without drinking water. Because the medicine can get stuck in the throat causing esophagitis.
  • Problems in the kidneys and urethra: it is possible to have a kidney stone, but it is very rare.
  • Hepatic effects: Affects liver function, but with very low frequency.

In case of overdose, cardiac conduction may decrease or convulsions may occur. You need to immediately take the patient to the nearest medical facility for timely treatment.

7. How to store medicine 

What you need to know about Praxilen (naftidrofuryl)

Store in a cool, dry place away from direct sunlight, at a temperature not exceeding 25°C.

The selling price at drugstores is about 125,000 VND / box / 20 tablets.

Complications from vascular occlusion are varied and serious. You should not subjectively buy drugs on your own, but need to see a specialist for timely examination and treatment to avoid more serious complications. Hopefully, the above article has provided you with the necessary knowledge about the drug Praxilen.

Pharmacist Nguyen Ngoc Cam Tien


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