What is Zyx? Uses, side effects and some notes when using Zyx

Zyx medicine 5mg is indicated for the treatment of allergic rhinitis, urticaria. In this article, SignsSymptomsList would like to share with readers the notes and how to use Zyx 5mg.

Zyx 5mg contains Levocetirizine dihydrochloride. This medication is used to treat chronic, seasonal allergic rhinitis and other allergic disorders.

What is Zyx?

Zyx film-coated tablets are indicated for the symptomatic treatment of chronic persistent allergic rhinitis, seasonal allergic rhinitis, sneezing, rhinorrhea, nasal itching, lacrimation, allergic conjunctivitis and urticaria Chronic idiopathic urticaria in adults and children from 6 years of age.

Dosage form: Film coated tablets.

Composition: Each Zyx 5mg tablet contains the main ingredient Levocetirizine dihydrochloride with the corresponding content of 5mg and other excipients according to the manufacturer's formula.

Zyx is available in the form of film-coated tablets

Uses of Zyx

Levocetirizine dihydrochloride effects

Levocetirizine dihydrochloride provides the following benefits:

  • Mechanism: Histamine is a mediator released from mast cells that binds to H1 receptors, causing anaphylaxis and allergic reactions. Levocetirizine competes directly with the H1-receptor, causing histamine to lose its binding site and become ineffective.
  • Rapid reduction of allergic diseases in the early stages.
  • A second-generation antihistamine, which crosses the blood-brain barrier less often and therefore has fewer central nervous system side effects than first-generation histamine.

Point

Zyx 5mg medicine is used for adults and children over 6 years old:

  • Treatment of persistent, persistent  allergic rhinitis .
  • Seasonal allergic rhinitis, changes in weather, sneezing, watery eyes, runny nose, itchy nose.
  • Allergic conjunctivitis.
  • Chronic urticaria of unknown cause.

Contraindications

Do not use Zyx 5mg for those who:

  • Hypersensitivity to Levocetirizine and other piperazine derivatives or to any of the excipients.
  • End stage kidney disease or on hemodialysis, children with kidney failure.
  • Renal patients with creatinine clearance < 10="" ml/min.="">
  • Do not use for children under 6 years old.
  • Diseases of galactose intolerance, lactase deficiency or glucose-galactose malabsorption. 
  • Patients with liver and kidney dysfunction.

How to take Zyx

User manual

Use orally.

Under no circumstances should you bite, chew or crush the tablet before taking it. Swallow the tablet whole with filtered or boiled water.

Time of use: Can be taken with or without meals.

Amount

Dosage depends on the type of disease:

  • Seasonal allergic rhinitis: 1 tablet / time / day, stop when the symptoms are gone, can continue when the symptoms recur. 
  • Persistent allergic rhinitis (symptoms > 4 days/week, lasting > 4 weeks): 1 tablet/time/day for 6 months combined with limiting patient exposure to allergens.
  • Urticaria and chronic allergic rhinitis: Take 1 tablet once a day for 1 year.
  • In patients with renal impairment, the dose should be adjusted according to the individual patient's renal creatinine clearance.

Dealing with drug overdose, missed dose

Missed dose: Take as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your usual dose. Do not double the dose to make up for the missed dose. 

Overdose: The drug affects the central nervous system, causing confusion, dizziness, headache, mild sedation, drowsiness. With anticholinergic effect will cause pupil dilation, itching, tachycardia, tremor, restlessness, urinary retention. Currently, there is no specific antidote to Levocetirizine. It is necessary to take the patient to the nearest medical facility for monitoring and symptomatic treatment. Gastric lavage may be considered if recently ingested.

Zyx is taken orally

Zyx side effects

Some of the specifically reported side effects are:

Frequent: 

  • Nervous system: Drowsiness, drowsiness, somnolence, dizziness, headache. 
  • Gastrointestinal: Dry mouth, nausea. 

Less common:

  • Nervous: Excitement, excitement.
  • Gastrointestinal: Abdominal pain, diarrhea.
  • Skin and subcutaneous tissue: Itching, rash. 
  • Body as a whole: Fatigue.

Rarely:

  • Allergies: Hypersensitivity, itching, edema, urticaria.
  • Respiratory: Shortness of breath.
  • Neurological: Movement disorder with convulsions, aggression or agitation.
  • Cardiovascular: Tachycardia. 
  • Liver: Hepatitis , abnormal liver function.
  • Body as a whole: Muscle aches and pains.

If you notice the above side effects, you should notify your doctor for timely treatment.

Interactions with other drugs:

  • Concomitant administration of Theophylline reduces the clearance of Levocetirizine.
  • Food can slow down the absorption of the drug. 
  • Ritonavir prolongs the half-life of Levocetirizine (53%), reduces clearance (29%), and increases the likelihood of adverse events.

Notes when using and storing Zyx

Use in pregnant and lactating women:

  • Pregnancy: The safety of levocetirizine in pregnant women has not been established. There is little clinical evidence for its use in this population. Animal studies have shown no adverse effects on pregnancy, embryo/fetal development or postnatal development. Check with your doctor before taking the medicine to make sure it's safe.
  • Lactation: Since cetirizine is an isomer of levocetirizine that has been reported to be present in human milk, levocetirizine is also expected to be present in breast milk. However, to be on the safe side, the drug should only be used when prescribed by a doctor.

For drivers and machine operators:

People using levocetirizine should be warned about drowsiness, fatigue, and exhaustion. Therefore, the drug is not safe and caution should be exercised when driving or operating machinery.

Caution should be exercised when using Zyx with people who often drive and operate machinery

Other special note:

Caution should be exercised in elderly patients with impaired renal function.

Storage conditions:

  • Store the medicine in a cool, dry place away from moisture and direct sunlight.
  • Storage temperature 30°C or less.
  • Keep out of reach of CHILDREN.

So the above article has helped you get more information about Zyx drug . We hope to help you choose the right medicine for you and your family. Good luck reading and don't forget to follow the next articles on SignsSymptomsList's website!



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